General Information:

Id: 122 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mammalia
review
Reference: Grimes CA and Jope RS(2001) The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling Prog. Neurobiol. 65: 391-426 [PMID: 11527574]

Interaction Information:

Comment Opposite to the inhibitory effect of complex formation with GBP, GSK3B activity is enhanced by binding to Axin, which is both a substrate for phosphorylation by GSK3B and enhances GSK3B-induced phosphorylation of beta-catenin.
Formal Description
Interaction-ID: 687

gene/protein

AXIN1

increases_activity of

gene/protein

GSK3B

Drugbank entries Show/Hide entries for AXIN1 or GSK3B