General Information:

Id: 122 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mammalia
review
Reference: Grimes CA and Jope RS(2001) The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling Prog. Neurobiol. 65: 391-426 [PMID: 11527574]

Interaction Information:

Comment GSK3B phosphorylates, deactivates, and induces nuclear export of NFATc, providing a mechanism by which calcium-calcineurin signaling and GSK3B could counteract each other to regulate NFATc activity.
Formal Description
Interaction-ID: 12947

gene/protein

GSK3B

decreases_activity of

gene/protein

NFATC1

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