General Information:

Id: 1,217 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
female
article
Reference: Riant E et al.(2009) Estrogens protect against high-fat diet-induced insulin resistance and glucose intolerance in mice Endocrinology 150: 2109-2117 [PMID: 19164473]

Interaction Information:

Comment Although the proinflammatory effect of E2 was abolished in visceral adipose tissue from chimeric mice grafted with bone marrow cells from ERalpha-deficient mice, the beneficial effect of the hormone on glucose tolerance was not altered, suggesting that the metabolic and inflammatory effects of estrogens can be dissociated.
Formal Description
Interaction-ID: 8213

drug/chemical compound

Estradiol

increases_activity of

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