General Information:

Id: 1,215 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Mus musculus
Reference: Su X et al.(2008) Synuclein activates microglia in a model of Parkinsons disease Neurobiol. Aging 29: 1690-1701 [PMID: 17537546]

Interaction Information:

Comment Activation of microglia is accompanied by alterations in cell surface receptor expression, increased reactive oxygen species (ROS) production and release of chemokines and cytokines, such as TNFalpha and IL1beta. (cited information)
Formal Description
Interaction-ID: 8162

increases_quantity of

drug/chemical compound

Reactive oxygen species

in brain