General Information:
Id: | 1,211 (click here to show other Interactions for entry) |
Diseases: |
Parkinson disease
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Homo sapiens | |
BTO:0000099 astrocyte; BTO:0002126 U-373MG cell | |
article | |
Reference: | Klegeris A et al.(2006) Alpha-synuclein and its disease-causing mutants induce ICAM-1 and IL-6 in human astrocytes and astrocytoma cells FASEB J. 20: 2000-2008 [PMID: 17012252] |
Interaction Information:
Comment | Increase of the inflammation markers, ICAM-1 and IL-6, after expression of alpha-synuclein is associated with activation of major mitogen-activated protein kinase (MAPK) pathways. |
Formal Description Interaction-ID: 8150 |
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Drugbank entries | Show/Hide entries for IL6 |