General Information:
Id: | 1,207 (click here to show other Interactions for entry) |
Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
Mus musculus | |
male | |
article | |
Reference: | Lumeng CN et al.(2007) Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity Diabetes 56: 16-23 [PMID: 17192460] |
Interaction Information:
Comment | Although CD14 and TNF-alpha were expressed at equal levels in resident and recruited adipose tissue macrophage (ATM) pools, IL-6, iNOS, and CCR2 were expressed at higher levels in the recruited ATMs. Expression of these inflammatory genes in both recruited and resident high-fat diet ATM populations were higher than ATMs from normal diet mice. This suggests that ATMs newly recruited to adipose tissue have an increased inflammatory capacity compared with resident ATMs. |
Formal Description Interaction-ID: 8095 |
|
Drugbank entries | Show/Hide entries for IL6 |