CIDeRGeneral Information:
| Id: | 1,207 (click here to show other Interactions for entry) |
| Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
| Mus musculus | |
| male | |
| article | |
| Reference: | Lumeng CN et al.(2007) Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity Diabetes 56: 16-23 [PMID: 17192460] |
Interaction Information:
| Comment | Although CD14 and TNF-alpha were expressed at equal levels in resident and recruited adipose tissue macrophage (ATM) pools, IL-6, iNOS, and CCR2 were expressed at higher levels in the recruited ATMs. Expression of these inflammatory genes in both recruited and resident high-fat diet ATM populations were higher than ATMs from normal diet mice. This suggests that ATMs newly recruited to adipose tissue have an increased inflammatory capacity compared with resident ATMs. |
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Formal Description Interaction-ID: 8095 |
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| Drugbank entries | Show/Hide entries for IL6 |