CIDeRGeneral Information:
| Id: | 1,204 (click here to show other Interactions for entry) |
| Diseases: |
Parkinson disease
|
| Mus musculus | |
| SNCA-inducible transgenic mice in which the PD-related A53T-SNCA is selectively expressed by astrocytes | |
| BTO:0000099 astrocyte | |
| article | |
| Reference: | Gu XL et al.(2010) Astrocytic expression of Parkinsons disease-related A53T alpha-synuclein causes neurodegeneration in mice Mol Brain 3: 12 [PMID: 20409326] |
Interaction Information:
| Comment | A significant increase of TNF-alpha, IL-1beta, and IL-6 expression was observed in the brainstem but not in the cerebral cortex of A53T mice. |
|
Formal Description Interaction-ID: 8102 |
gene/protein mutant increases_expression of gene/protein |
| Drugbank entries | Show/Hide entries for IL6 |