General Information:

Id: 1,204 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Mus musculus
SNCA-inducible transgenic mice in which the PD-related A53T-SNCA is selectively expressed by astrocytes
BTO:0000099 astrocyte
article
Reference: Gu XL et al.(2010) Astrocytic expression of Parkinsons disease-related A53T alpha-synuclein causes neurodegeneration in mice Mol Brain 3: 12 [PMID: 20409326]

Interaction Information:

Comment A significant increase of TNF-alpha, IL-1beta, and IL-6 expression was observed in the brainstem but not in the cerebral cortex of A53T mice.
Formal Description
Interaction-ID: 8102

gene/protein mutant

SNCA-p.A53T

increases_expression of

gene/protein

IL6

in the brainstem but not in the cerebral cortex of A53T mice
Drugbank entries Show/Hide entries for IL6