General Information:
Id: | 1,202 (click here to show other Interactions for entry) |
Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
Mus musculus | |
male | |
article | |
Reference: | Arkan MC et al.(2005) IKK-beta links inflammation to obesity-induced insulin resistance Nat. Med. 11: 191-198 [PMID: 15685170] |
Interaction Information:
Comment | mRNAs encoding IL-1alpha, IL-1beta, IL-6 and RANTES were elevated in livers from Ikbkb F/F mice (homozygous for the nondeleted Ikbkb allele flanked by 10xP sites) on high fat diet. This increase was markedly attenuated in Ikbkb-Delta-hep mice (mice lacking Ikbkb in hepatocytes). |
Formal Description Interaction-ID: 8026 |
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Drugbank entries | Show/Hide entries for IL6 |