Search is restricted to the following diseases: All diseases
General Information:
Id:
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11
(click here to show other Interactions for entry)
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Diseases:
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Parkinson disease
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Mus musculus
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primary cortical neurons
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article
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Reference:
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Smith WW et al.(2005) Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration. Proc. Natl. Acad. Sci. U.S.A. 102
[PMID: 16352719]
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Interaction Information:
Comment
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Transfection of LRRK2 mutants R1441C, Y1699C or G2019S into primary cortical neuronal cultures leads to cell death.
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Formal Description Interaction-ID: 34
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