General Information:

Id: 1,199 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Reference: Zhang W et al.(2005) Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinsons disease FASEB J. 19: 533-542 [PMID: 15791003]

Interaction Information:

Comment NADPH-oxidase has been determined to be one of the major sources for production of ROS or related reactive nitric species in activated microglia. (cited information)
Formal Description
Interaction-ID: 8018


NADPH oxidase complex

increases_quantity of

drug/chemical compound

Reactive oxygen species

in activated microglia cells