Welcome to cider

Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	11,842 (click here to show other Interactions for entry)
Diseases:	Endocrine
Organism:	Mus musculus
Gender:	male
Tissue/Cell line:	kidney
Publication type:	article
Reference:	Grobe N et al.(2013) Identification of prolyl carboxypeptidase as an alternative enzyme for processing of renal angiotensin II using mass spectrometry Am. J. Physiol. 304: C945-C953 [PMID: 23392115]

Interaction Information:

Comment	ACE2 metabolizes ANG II to Ang 1-7 in the kidney at neutral and basic pH, while prolylcarboxypeptidase catalyzes the same reaction at acidic pH.
Formal Description Interaction-ID: 116926	gene/protein PRCP decreases_quantity of gene/protein Angiotensin II in kidney ; at acidic pH

Home
Contact

The Helmholtz Zentrum München Imprint and Privacy Policy apply.

© 2013 - Helmholtz Zentrum München - German Research Center for Environmental Health (GmbH) Ingolstädter Landstraße 1, D-85764 Neuherberg, Germany

Disclaimer: IBIS Databases and associated information are protected by copyright. This server and its associated data and services are for academic, non-commercial use only. The Helmholtz Zentrum München has no liability for the use of results, data or information which have been provided through this server. Neither the use for commercial purposes, nor the redistribution of IBIS database files to third parties nor the distribution of parts of files or derivative products to any third parties is permitted. Commercial users shall contact the Helmholtz Zentrum München for a separate users license.