General Information:

Id: 11,837 (click here to show other Interactions for entry)
Diseases: Endocrine
Homo sapiens
CHO cells transfected with human genes
article
Reference: Donoghue M et al.(2000) A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9 Circ. Res. 87: E1-E9 [PMID: 10969042]

Interaction Information:

Comment ACE2 and ACE catalytic activity has been analyzed in CHO cells expressing human ACE2. ACE converted the decapeptide Ang I to Ang II. ACE2, in contrast, converted Ang I to the nonapeptide Ang1-9.
Formal Description
Interaction-ID: 116868

gene/protein

Angiotensin I

increases_quantity of

gene/protein

Angiotensin (1-9)

via the catalytic activity of ACE2