CIDeRGeneral Information:
| Id: | 11,837 |
| Diseases: |
Endocrine
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| Homo sapiens | |
| CHO cells transfected with human genes | |
| article | |
| Reference: | Donoghue M et al.(2000) A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9 Circ. Res. 87: E1-E9 [PMID: 10969042] |
Interaction Information:
| Comment | ACE2 and ACE catalytic activity has been analyzed in CHO cells expressing human ACE2. ACE converted the decapeptide Ang I to Ang II. ACE2, in contrast, converted Ang I to the nonapeptide Ang1-9. |
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Formal Description Interaction-ID: 116863 |
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| Drugbank entries | Show/Hide entries for ACE |
| Comment | ACE2 and ACE catalytic activity has been analyzed in CHO cells expressing human ACE2. ACE converted the decapeptide Ang I to Ang II. ACE2, in contrast, converted Ang I to the nonapeptide Ang1-9. |
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Formal Description Interaction-ID: 116866 |
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| Drugbank entries | Show/Hide entries for ACE |
| Comment | ACE2 and ACE catalytic activity has been analyzed in CHO cells expressing human ACE2. ACE converted the decapeptide Ang I to Ang II. ACE2, in contrast, converted Ang I to the nonapeptide Ang1-9. |
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Formal Description Interaction-ID: 116867 |
gene/protein increases_quantity of gene/protein |
| Comment | ACE2 and ACE catalytic activity has been analyzed in CHO cells expressing human ACE2. ACE converted the decapeptide Ang I to Ang II. ACE2, in contrast, converted Ang I to the nonapeptide Ang1-9. |
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Formal Description Interaction-ID: 116868 |
gene/protein increases_quantity of gene/protein |
| Comment | ACE2 and ACE catalytic activity has been analyzed in CHO cells expressing human ACE2. ACE converted the decapeptide Ang I to Ang II. ACE2, in contrast, converted Ang I to the nonapeptide Ang1-9. |
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Formal Description Interaction-ID: 116869 |
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| Drugbank entries | Show/Hide entries for ACE2 |
| Comment | ACE2 and ACE catalytic activity has been analyzed in CHO cells expressing human ACE2. ACE converted the decapeptide Ang I to Ang II. ACE2, in contrast, converted Ang I to the nonapeptide Ang1-9. |
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Formal Description Interaction-ID: 116870 |
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| Drugbank entries | Show/Hide entries for ACE2 |
| Comment | Incubation of Ang1-9 with ACE in vitro generated Ang1-7 and Ang1-5, apparently by sequential cleavage of C-terminal dipeptides. |
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Formal Description Interaction-ID: 116873 |
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| Drugbank entries | Show/Hide entries for ACE |
| Comment | Incubation of Ang1-9 with ACE in vitro generated Ang1-7 and Ang1-5, apparently by sequential cleavage of C-terminal dipeptides. |
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Formal Description Interaction-ID: 116874 |
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| Drugbank entries | Show/Hide entries for ACE |
| Comment | Incubation of Ang1-9 with ACE in vitro generated Ang1-7 and Ang1-5, apparently by sequential cleavage of C-terminal dipeptides. |
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Formal Description Interaction-ID: 116875 |
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| Drugbank entries | Show/Hide entries for ACE |
| Comment | Incubation of Ang1-9 with ACE in vitro generated Ang1-7 and Ang1-5, apparently by sequential cleavage of C-terminal dipeptides. |
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Formal Description Interaction-ID: 116876 |
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| Drugbank entries | Show/Hide entries for ACE |
| Comment | Incubation of Ang1-9 with ACE in vitro generated Ang1-7 and Ang1-5, apparently by sequential cleavage of C-terminal dipeptides. |
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Formal Description Interaction-ID: 116883 |
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| Comment | Incubation of Ang1-9 with ACE in vitro generated Ang1-7 and Ang1-5, apparently by sequential cleavage of C-terminal dipeptides. |
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Formal Description Interaction-ID: 116884 |
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