General Information:

Id: 11,717 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
review
Reference: Graus-Nunes F and Souza-Mello V(2019) The renin-angiotensin system as a target to solve the riddle of endocrine pancreas homeostasis Biomed. Pharmacother. 109: 639-645 [PMID: 30404071]

Interaction Information:

Comment ANG2 interaction with AT1R leads to vasoconstriction, cell growth, inflammation, fibrosis and oxidative stress.
Formal Description
Interaction-ID: 116411

gene/protein

AGTR1

increases_activity of

process

inflammatory response

Drugbank entries Show/Hide entries for AGTR1
Comment ANG2 interaction with AT1R leads to vasoconstriction, cell growth, inflammation, fibrosis and oxidative stress.
Formal Description
Interaction-ID: 116413

gene/protein

AGTR1

increases_activity of

process

response to oxidative stress

Drugbank entries Show/Hide entries for AGTR1
Comment AT2R is involved in vasodilatation and regulates pancreas development.
Formal Description
Interaction-ID: 116414

gene/protein

AGTR2

increases_activity of

process

vasodilation

Drugbank entries Show/Hide entries for AGTR2