General Information:

Id: 11,684 (click here to show other Interactions for entry)
Diseases: COVID-19
Cardiovascular disease
Rattus norvegicus
article
Reference: [PMID: 26171856]

Interaction Information:

Comment Male rats exhibited higher ACE2 and ACE ventricular activity than the female rats. Gonadectomy, withdrawal of testosterone, promoted opposite responses in the activity of both enzymes.
Formal Description
Interaction-ID: 116070

phenotype

sex, male

increases_activity of

gene/protein

ACE2

in cardiac tissue; compared to female
Drugbank entries Show/Hide entries for ACE2
Comment Male rats exhibited higher ACE2 and ACE ventricular activity than the female rats. Gonadectomy, withdrawal of testosterone, promoted opposite responses in the activity of both enzymes.
Formal Description
Interaction-ID: 117240

phenotype

sex, male

increases_activity of

gene/protein

ACE

in cardiac tissue; compared to female
Drugbank entries Show/Hide entries for ACE