General Information:

Id: 1,166
Diseases: Schizophrenia - [OMIM]
Homo sapiens
article
Reference: Muller N et al.(2010) Celecoxib treatment in an early stage of schizophrenia: results of a randomized, double-blind, placebo-controlled trial of celecoxib augmentation of amisulpride treatment Schizophr. Res. 121: 118-124 [PMID: 20570110]

Interaction Information:

Comment Forty-nine patients diagnosed with schizophrenia were randomly assigned. They were treated either with amisulpride (200-1000mg) plus anti-inflammmatory celecoxib (400mg) or disulphide (200-1000mg) plus placebo. A significantly better outcome was observed in the patient group treated with amisulpride plus celecoxib compared to the group with amisulpride plus placebo.
Formal Description
Interaction-ID: 7676

drug/chemical compound

Celecoxib

decreases_activity of

gene/protein

PTGS2

Drugbank entries Show/Hide entries for Celecoxib or PTGS2
Comment Forty-nine patients diagnosed with schizophrenia were randomly assigned. They were treated either with amisulpride (200-1000mg) plus anti-inflammatory celecoxib (400mg) or disulphide (200-1000mg) plus placebo. A significantly better outcome was observed in the patient group treated with amisulpride plus celecoxib compared to the group with amisulpride plus placebo.
Formal Description
Interaction-ID: 7678

drug/chemical compound

Amisulpride

decreases_activity of

gene/protein

DRD2

Drugbank entries Show/Hide entries for Amisulpride or DRD2
Comment Forty-nine patients diagnosed with schizophrenia were randomly assigned. They were treated either with amisulpride (200-1000mg) plus anti-inflammatory celecoxib (400mg) or disulphide (200-1000mg) plus placebo. A significantly better outcome was observed in the patient group treated with amisulpride plus celecoxib compared to the group with amisulpride plus placebo.
Formal Description
Interaction-ID: 7680

drug/chemical compound

Amisulpride

decreases_activity of

gene/protein

DRD3

Drugbank entries Show/Hide entries for Amisulpride or DRD3
Comment Forty-nine patients diagnosed with schizophrenia were randomly assigned. They were treated either with amisulpride (200-1000mg) plus anti-inflammatory celecoxib (400mg) or disulphide (200-1000mg) plus placebo. A significantly better outcome was observed in the patient group treated with amisulpride plus celecoxib compared to the group with amisulpride plus placebo.
Formal Description
Interaction-ID: 7687

drug/chemical compound

Amisulpride

decreases_activity of

disease

Schizophrenia

Drugbank entries Show/Hide entries for Amisulpride
Comment Forty-nine patients diagnosed with schizophrenia were randomly assigned. They were treated either with amisulpride (200-1000mg) plus anti-inflammatory celecoxib (400mg) or disulphide (200-1000mg) plus placebo. A significantly better outcome was observed in the patient group treated with amisulpride plus celecoxib compared to the group with amisulpride plus placebo.
Formal Description
Interaction-ID: 7688

drug/chemical compound

Celecoxib

decreases_activity of

disease

Schizophrenia

Drugbank entries Show/Hide entries for Celecoxib