General Information:

Id: 1,149 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
male
article
Reference: Uysal KT et al.(1997) Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. Nature 389: 610-614 [PMID: 9335502]

Interaction Information:

Comment The TNFalpha-deficient obese mice had lower levels of circulating free fatty acids, and were protected from the obesity-related reduction in the insulin receptor signalling in muscle and fat tissues.
Formal Description
Interaction-ID: 7520

gene/protein

TNF

NOT affects_activity of

after diet-induced obesity
Drugbank entries Show/Hide entries for TNF