General Information:

Id: 1,148 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
article
Reference: Peraldi P et al.(1996) Tumor necrosis factor (TNF)-alpha inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase J Biol Chem 271 [PMID: 8662983]

Interaction Information:

Comment TNF-alpha inhibits insulin signaling in 3T3-L1 adipocytes and myeloid 32D cells.
Formal Description
Interaction-ID: 7487

gene/protein

TNF

decreases_activity of

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