General Information:

Id: 1,139 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
article
Reference: Baumann CA et al.(2000) CAP defines a second signalling pathway required for insulin-stimulated glucose transport. Nature 407: 202-207 [PMID: 11001060]

Interaction Information:

Comment Insulin stimulated the translocation of GLUT4-EGFP to the plasma membrane in cells transfected with CAP, as detected by the presence of a continuous rim of cell-surface EGFP fluorescence. In contrast, expression of CAP-delta-SH3 markedly inhibited GLUT4-EGFP translocation to the cell surface in response to insulin.
Formal Description
Interaction-ID: 7458

gene/protein

CAP1

affects_activity of

process

glucose import