General Information:

Id: 111 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
BTO:0001279 spinal cord
article
Reference: Nishitoh H et al.(2008) ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1 Genes Dev. 22: 1451-1464 [PMID: 18519638]

Interaction Information:

Comment SOD1(G93A) exists mainly in the cytosol, and some fraction of SOD1mut attaches to the cytosolic surface of the ER.
Formal Description
Interaction-ID: 379

gene/protein mutant

SOD1-p.G93A

is localized in

cellular component

cytoplasm

mainly