General Information:

Id: 1,105 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Mammalia
article/cited
Reference: Kim SR et al.(2010) Prothrombin kringle-2 induces death of mesencephalic dopaminergic neurons in vivo and in vitro via microglial activation J. Neurosci. Res. 88: 1537-1548 [PMID: 20025058]

Interaction Information:

Comment Activated microglia produce inflammatory mediators, such as inducible nitric oxide synthase, cyclooxygenase-2 and proinflammatory cytokines, including interleukin 1, IL-6 and tumor necrosis factor alpha. (cited information)
Formal Description
Interaction-ID: 7017

process

microglial cell activation

increases_quantity of

gene/protein

IL6

Drugbank entries Show/Hide entries for IL6