General Information:

Id: 1,102 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
peripheral blood mononuclear cells (PBMCs) BTO:0001025 from AD patients
article
Reference: Candore G et al.(2010) Inflammation, cytokines, immune response, apolipoprotein E, cholesterol, and oxidative stress in Alzheimer disease: therapeutic implications Rejuvenation Res 13: 301-313 [PMID: 20462385]

Interaction Information:

Comment Cytokines (IL-1beta, IL-1ra, IL-6, IFN-gamma, TNF-alpha, IL-10, IL-8) whose secretion by Alzheimer's disease peripheral blood mononuclear cells is significantly increased when stimulated with recombinant Abeta42 with respect to control cultures.
Formal Description
Interaction-ID: 6995

increases_activity of

in PBMCs from AD patients compared to PBMCs in healthy controls