General Information:

Id: 1,092 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Reference: de Luca C and Olefsky JM(2008) Inflammation and insulin resistance FEBS Lett. 582: 97-105 [PMID: 18053812]

Interaction Information:

Comment The induction of ER stress induces insulin resistance via JNK-mediated serine phosphorylation of IRS1 in cultured liver cells.
Formal Description
Interaction-ID: 7354

increases_activity of


Insulin resistance

via JNK-mediated Ser phosphorylation of IRS1