General Information:

Id: 1,092 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mammalia
article
Reference: de Luca C and Olefsky JM(2008) Inflammation and insulin resistance FEBS Lett. 582: 97-105 [PMID: 18053812]

Interaction Information:

Comment In addition to adipocytes, Pparg is also expressed in macrophages where it negatively regulates a large set of inflammatory pathway genes by a unique transrepression mechanism.
Formal Description
Interaction-ID: 7317

gene/protein

PPARG

decreases_activity of

in macrophages
Drugbank entries Show/Hide entries for PPARG