General Information:

Id: 1,092 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mammalia
article
Reference: de Luca C and Olefsky JM(2008) Inflammation and insulin resistance FEBS Lett. 582: 97-105 [PMID: 18053812]

Interaction Information:

Comment Socs1 and Socs3, which are induced in inflammation, promote the ubiquitylation and subsequent degradation of IRS1.
Formal Description
Interaction-ID: 6985

increases_activity of

gene/protein

SOCS1