General Information:

Id: 1,092 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mammalia
article
Reference: de Luca C and Olefsky JM(2008) Inflammation and insulin resistance FEBS Lett. 582: 97-105 [PMID: 18053812]

Interaction Information:

Comment Activation of the insulin receptor leads to tyrosine phosphorylation of IRS1 thereby initiating signal transduction.
Formal Description
Interaction-ID: 6981

protein modification

IRS1-phosTyr

increases_activity of