General Information:

Id: 1,086 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Mus musculus
BTO:0000099 astrocyte
article
Reference: Waak J et al.(2009) Regulation of astrocyte inflammatory responses by the Parkinsons disease-associated gene DJ-1 FASEB J. 23: 2478-2489 [PMID: 19276172]

Interaction Information:

Comment Il-6 and COX-2 expression was induced after LPS stimulation to significantly higher levels in Dj-1-/- astrocytes compared with wild-type controls.
Formal Description
Interaction-ID: 6939

drug/chemical compound

Lipopolysaccharide

increases_expression of

gene/protein

IL6

Drugbank entries Show/Hide entries for IL6