General Information:

Id: 1,086 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Mus musculus
BTO:0000099 astrocyte
article
Reference: Waak J et al.(2009) Regulation of astrocyte inflammatory responses by the Parkinsons disease-associated gene DJ-1 FASEB J. 23: 2478-2489 [PMID: 19276172]

Interaction Information:

Comment A second LPS-inducible enzyme generating proinflammatory mediators is COX-2, which produces prostaglandin E2 and is believed to contribute to neuroinflammatory processes in PD, like iNOS.
Formal Description
Interaction-ID: 6937

increases_activity of

disease

Parkinson disease