General Information:

Id: 1,081 (click here to show other Interactions for entry)
Diseases: Neurological
Mus musculus
BTO:0001958 embryonic fibroblast cell line; BTO:0000944 NIH-3T3 cell
Reference: Stambolic V et al.(1998) Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell 95: 29-39 [PMID: 9778245]

Interaction Information:

Comment PTEN-deficient mouse embryonic fibroblasts exhibit decreased sensitivity to apoptosis. Expression of exogenous mPTEN restores sensitivity to apoptosis.
Formal Description
Interaction-ID: 6846



increases_activity of