General Information:

Id: 103 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
article
Reference: Alessi DR et al.(1996) Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J. 15: 6541-6551 [PMID: 8978681]

Interaction Information:

Comment Active AKT1 (phosphorylated at Ser-473 and Thr-308) reduces activity of GSK3B by phosphorylation at Ser9.
Formal Description
Interaction-ID: 350

protein modification

AKT1-phosSer473Thr308

decreases_activity of

gene/protein

GSK3B

by GSK3B phosphorylation at Ser9; AKT1-phosSer473Thr308 = active AKT1;
Drugbank entries Show/Hide entries for GSK3B