General Information:

Id: 1,034 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Drosophila melanogaster
Vap-33-1 wt (dVAP) or Vap-33-1(P58S) (P58S dVAP) transgenic fruit fly
Reference: Tsuda H et al.(2008) The amyotrophic lateral sclerosis 8 protein VAPB is cleaved, secreted, and acts as a ligand for Eph receptors. Cell 133: 963-977 [PMID: 18555774]

Interaction Information:

Comment P58S dVAP accumulates in and disrupts the ER, and induces an unfolded protein response.
Formal Description
Interaction-ID: 6499

gene/protein mutant


affects_activity of