General Information:

Id: 1,026 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mus musculus
article
Reference: Zabolotny JM et al.(2008) Protein-tyrosine phosphatase 1B expression is induced by inflammation in vivo. J. Biol. Chem. 283 [PMID: 18281274]

Interaction Information:

Comment TNF-alpha mRNA levels were increased in adipose tissue of mice with diet-induced obesity compared with chow-fed mice at both 15 and 20 weeks, but the magnitude of increase was substantially higher in mice at 20 weeks.
Formal Description
Interaction-ID: 6453

phenotype

obesity, high-fat diet-induced

increases_expression of

gene/protein

TNF

Drugbank entries Show/Hide entries for TNF