General Information:

Id: 1,023 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Rattus norvegicus
Sprague-Dawley rat pups
primary neuronal culture
article
Reference: Chen J et al.(2005) SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling J. Biol. Chem. 280 [PMID: 16183991]

Interaction Information:

Comment SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling.
Formal Description
Interaction-ID: 6418

gene/protein

SIRT1

decreases_activity of

process

NF-kappaB signaling