General Information:

Id: 1,020 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Homo sapiens
BTO:0000007 HEK-293 cell
article
Reference: Lin JH et al.(2007) IRE1 signaling affects cell fate during the unfolded protein response. Science 318: 944-949 [PMID: 17991856]

Interaction Information:

Comment Aktivation of PERK during ER stress resulted in the accumulation of phosphorylated elF2alpha (EIF2S1) as well as continuous production of ATF4 and its transcriptional target Chop (DDIT3).
Formal Description
Interaction-ID: 6401

increases_activity of

gene/protein

DDIT3