General Information:

Id: 1,020 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Homo sapiens
BTO:0000007 HEK-293 cell
Reference: Lin JH et al.(2007) IRE1 signaling affects cell fate during the unfolded protein response. Science 318: 944-949 [PMID: 17991856]

Interaction Information:

Comment In contrast to IRE1 and ATF6, PERK (EIF2AK3) activation is largely sustained with unmitigated ER stress.
Formal Description
Interaction-ID: 6398

increases_activity of