General Information:

Id: 1,020 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Homo sapiens
BTO:0000007 HEK-293 cell
article
Reference: Lin JH et al.(2007) IRE1 signaling affects cell fate during the unfolded protein response. Science 318: 944-949 [PMID: 17991856]

Interaction Information:

Comment Induction of BiP (HSPA5) mRNA, encoding an HSP70-class ER chaperone that is transcriptionally regulated by both ATF6f and XBP-1s (spliced), peaked at 8 hours after drug treatment and then declined to near preinduction levels.
Formal Description
Interaction-ID: 6396

increases_expression of

gene/protein

HSPA5

Drugbank entries Show/Hide entries for HSPA5