General Information:

Id: 1,020 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Homo sapiens
BTO:0000007 HEK-293 cell
Reference: Lin JH et al.(2007) IRE1 signaling affects cell fate during the unfolded protein response. Science 318: 944-949 [PMID: 17991856]

Interaction Information:

Comment ER stress (by thapsigargin) induces the cleavage of ATF6. The cytosolic fragment ATF6f is the active form of the transcription activator. ATF6f diminishes 20 hours after induction of ER stress.
Formal Description
Interaction-ID: 6368

increases_activity of