General Information:

Id: 1,005 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Rattus norvegicus
BTO:0002393 N-27 cell
article
Reference: Zhou W and Freed CR(2005) DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity J. Biol. Chem. 280 [PMID: 16227205]

Interaction Information:

Comment DJ-1 significantly reduced total cellular ROS levels after oxidative stress compared with control. The L166P DJ-1 had no effect on ROS.
Formal Description
Interaction-ID: 6282

gene/protein

PARK7

decreases_quantity of

drug/chemical compound

Reactive oxygen species

after oxidative stress
Drugbank entries Show/Hide entries for PARK7
Comment DJ-1 significantly reduced total cellular ROS levels after oxidative stress compared with control. The L166P DJ-1 had no effect on ROS.
Formal Description
Interaction-ID: 6283

gene/protein mutant

PARK7-p.L166P

NOT decreases_quantity of

drug/chemical compound

Reactive oxygen species

after oxidative stress