General Information:

Id: 1,005 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Rattus norvegicus
BTO:0002393 N-27 cell
article
Reference: Zhou W and Freed CR(2005) DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity J. Biol. Chem. 280 [PMID: 16227205]

Interaction Information:

Comment WT DJ-1 significantly increased GCL enzymatic activity under oxidative stress, whereas GS enzymatic activity was not changed.
Formal Description
Interaction-ID: 6278

gene/protein

PARK7

increases_activity of

gene/protein

GCLC

under oxidative stress conditions
Drugbank entries Show/Hide entries for PARK7 or GCLC