General Information:

Id: 1,005 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Rattus norvegicus
BTO:0002393 N-27 cell
article
Reference: Zhou W and Freed CR(2005) DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity J. Biol. Chem. 280 [PMID: 16227205]

Interaction Information:

Comment Overexpression of WT DJ-1 did not protect N27 cells against cell toxicity caused by the proteasome inhibitor lactacystin, indicating that the action of DJ-1 has some metabolic specificity.
Formal Description
Interaction-ID: 6272

gene/protein

PARK7

NOT decreases_activity of

drug/chemical compound

Lactacystin

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